Wrinkles in the skin due to sun damage and the aging process can be treated by injection. Fat and collagen are the most common substances used for replacing volume lost due to these forces. Previously, free silicone was injected but has been abandoned by the medical community due to problems with migration and uneven distribution. The drawback to fat and collagen injection has been their unreliable longevity. A new substance, hyaluronic acid, lasts 6 months or longer. Hyaluronic acid is found in the human body naturally, perhaps accounting for its long duration of action. Restylane is one tradename for hyaluronic acid. This may fill a long sought after role of a filler agent with an acceptable length of duration.
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